NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
- OUT: Derrick Williams (calf)
- OUT: Tyler Wolff (knee)
- QUESTIONABLE: Jamal Thiaré (hamstring)
Austin FC
- QUESTIONABLE: Guilherme Biro (hamstring)
- QUESTIONABLE: Ethan Finlay (hamstring)
- OUT: Brandon Cambridge (ankle)
- OUT: Liel Abada (thigh)
- OUT: Chase Gasper (leg)
- OUT: Tobias Salquist (leg)
- QUESTIONABLE: Maren Haile-Selassie (leg)
- OUT: Aaron Boupendza (jaw)
- OUT: Alvas Powell (hamstring)
- OUT: DeAndre Yedlin (hip)
- QUESTIONABLE: Corey Baird (hip)
Colorado Rapids
- OUT: Daniel Chacón (knee)
- OUT: Kimani Stewart-Baynes (groin)
- OUT: Evan Bush (arm)
- QUESTIONABLE: Jacen Russell-Rowe (knee)
FC Dallas
- Matchday 14 bye
D.C. United
- OUT: Conner Antley (knee)
- OUT: Russell Canouse (not due to injury)
Houston Dynamo FC
- OUT: Nelson Quiñónes (knee)
- OUT: Sebastian Ferreira (lower body)
- OUT: Daniel Steres (hip)
- QUESTIONABLE: Franco Escobar (lower body)
- OUT: Lorenzo Dellavalle (right knee)
- OUT: Ryan Hollingshead (neck)
- OUT: David Martinez (back)
- OUT: None
Inter Miami CF
- OUT: Facundo FarÃas (knee)
- OUT: Ian Fray (knee)
- OUT: Diego Gómez (ankle)
- OUT: Federico Redondo (knee)
- OUT: Robbie Robinson (knee)
- QUESTIONABLE: Lionel Messi (leg)
Minnesota United FC
- OUT: Jordan Adebayo-Smith (ankle)
- OUT: Hugo Bacharach (knee)
- OUT: Hassani Dotson (thigh)
- OUT: Moses Nyeman (thigh)
- OUT: Emanuel Reynoso (not due to injury)
- OUT: Matias Coccaro (knee)
- OUT: Grayson Doody (ankle)
- OUT: Raheem Edwards (abdomen)
- OUT: Ousman Jabang (adductor)
- OUT: Lassi Lappalainen (illness)
- OUT: Josef Martinez (knee)
- OUT: Mahala Opoku (ankle)
- OUT: Nathan Saliba (hip)
Nashville SC
- OUT: Lukas MacNaughton (ankle)
- OUT: Randall Leal (hip)
- QUESTIONABLE: Tyler Boyd (hip)
- QUESTIONABLE: Shaq Moore (hip)
- QUESTIONABLE: Walker Zimmerman (knee)
- Matchday 14 bye
New York City FC
- OUT: Rio Hope-Gund (leg)
- OUT: Maxi Moralez (knee)
New York Red Bulls
- OUT: Ronald Donkor (hip)
- OUT: Roald Mitchell (knee)
- OUT: Serge Ngoma (knee)
- OUT: Peter Stroud (ankle)
Orlando City SC
- OUT: Ramiro Enrique (ankle)
- OUT: Mikey Halliday (knee)
- OUT: Robin Jansson (ankle)
- OUT: Tahir Reid-Brown (thigh)
- QUESTIONABLE: Rafael Santos (shoulder)
Philadelphia Union
- OUT: Isaiah LeFlore (knee)
- OUT: Holden Trent (finger)
- QUESTIONABLE: Cavan Sullivan (hip)
- QUESTIONABLE: Andre Blake (knee)
Portland Timbers
- OUT: Miguel Araujo (leg)
- OUT: Claudio Bravo (lower leg)
- OUT: Marvin Loria (knee)
- QUESTIONABLE: Dairon Asprilla (leg)
- QUESTIONABLE: Kamal Miller (leg)
Real Salt Lake
- OUT: Kevin Bonilla (knee)
- OUT: Zavier Gozo (concussion)
- OUT: Erik Holt (hamstring)
- OUT: Pablo Ruiz (knee)
- OUT: Marcelo Silva (hamstring)
- QUESTIONABLE: Bode Hidalgo (hamstring)
- QUESTIONABLE: Bryan Oviedo (calf)
- QUESTIONABLE: Alex Katranis (adductor)
- OUT: Daniel Britto (lower body)
- OUT: JT Marcinkowski (knee)
- OUT: Jamar Ricketts (lower body)
- OUT: Josh Atencio (hamstring)
- OUT: Nathan (quad)
- OUT: Braudilio Rodrigues (hamstring)
- QUESTIONABLE: Pedro de la Vega (hamstring)
- QUESTIONABLE: Yeimar Gómez Andrade (quad)
- QUESTIONABLE: Raúl RuidÃaz (foot)
- QUESSTIONABLE: Obed Vargas (calf)
Sporting Kansas City
- Matchday 14 bye
- QUESTIONABLE: Josh Yaro (hamstring)
- QUESTIONABLE: Eduard Löwen (hamstring)
Toronto FC
- OUT: Jahkeele Marshall-Rutty (thigh)
- OUT: Shane O’Neill (thigh)
- OUT: Jonathan Osorio (thigh)
- OUT: Brandon Servania (knee)
Vancouver Whitecaps FC
- OUT: Sam Adekugbe (calf)
- OUT: Damir Kreilach (ankle)
