NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
- OUT: Thiago Almada (calf)
- OUT: Giorgos Giakoumakis (hamstring)
- OUT: Derrick Williams (calf)
- OUT: Tyler Wolff (knee)
Austin FC
- QUESTIONABLE: Guilherme Biro (hamstring)
- QUESTIONABLE: Ethan Finlay (hamstring)
- OUT: Liel Abada (thigh)
- OUT: Jere Uronen (thigh)
- QUESTIONABLE: Brandon Cambridge (ankle)
- OUT: Chase Gasper (leg)
- OUT: Tobias Salquist (leg)
- OUT: Aaron Boupendza (jaw)
- OUT: Alvas Powell (hamstring)
- OUT: DeAndre Yedlin (hip)
- QUESTIONABLE: Corey Baird (hip)
Colorado Rapids
- OUT: Daniel Chacón (knee)
- OUT: Kimani Stewart-Baynes (groin)
- QUESTIONABLE: Djordje Mihailovic (heel)
- OUT: Evan Bush (arm)
- QUESTIONABLE: Cucho Hernandez (back)
- QUESTIONABLE: Jacen Russell-Rowe (knee)
FC Dallas
- OUT: Paul Arriola (calf)
- OUT: Liam Fraser (thigh)
- OUT: Asier Illarramendi (glute)
- OUT: Geovane Jesus (knee)
- OUT: Amet Korça (groin)
- OUT: Paxton Pomykal (knee)
- OUT: Alan Velasco (knee)
D.C. United
- OUT: Conner Antley (knee)
- OUT: Russell Canouse (not due to injury)
Houston Dynamo FC
- OUT: Sebastian Ferreira (lower body)
- OUT: Nelson Quiñónes (knee)
- QUESTIONABLE: Daniel Steres (hip)
- QUESTIONABLE: Franco Escobar (lower body)
- Matchday 15 bye
- QUESTIONABLE: Joseph Paintsil (hamstring)
Inter Miami CF
- OUT: Facundo FarÃas (knee)
- OUT: Diego Gómez (ankle)
- OUT: Federico Redondo (knee)
- OUT: Robbie Robinson (knee)
- QUESTIONABLE: Ian Fray (knee)
Minnesota United FC
- OUT: Jordan Adebayo-Smith (ankle)
- OUT: Hugo Bacharach (knee)
- OUT: Hassani Dotson (thigh)
- OUT: Moses Nyeman (thigh)
- OUT: Emanuel Reynoso (not due to injury)
- OUT: Matias Coccaro (knee)
- OUT: Raheem Edwards (abdomen)
- OUT: Ousman Jabang (adductor)
- OUT: Lassi Lappalainen (hip)
- OUT: Josef Martinez (knee)
- OUT: Mahala Opoku (ankle)
- OUT: Nathan Saliba (adductor)
- OUT: Mason Toye (hamstring)
Nashville SC
- OUT: Randall Leal (hip)
- OUT: Lukas MacNaughton (ankle)
- QUESTIONABLE: Tyler Boyd (hip)
- QUESTIONABLE: Shaq Moore (hip)
- QUESTIONABLE: Dru Yearwood (ankle)
- QUESTIONABLE: Walker Zimmerman (knee)
- OUT: Brandon Bye (knee)
- OUT: Nacho Gil (knee)
- OUT: Tommy McNamara (hamstring)
- OUT: Peyton Miller (foot)
- QUESTIONABLE: Dylan Borrero (knee)
- QUESTIONABLE: DeJuan Jones (hamstring)
- QUESTIONABLE: Jonathan Mensah (hamstring)
- QUESTIONABLE: Ryan Spaulding (illness)
New York City FC
- OUT: Rio Hope-Gund (leg)
- OUT: Maxi Moralez (knee)
New York Red Bulls
- OUT: Ronald Donkor (hip)
- OUT: Roald Mitchell (knee)
- OUT: Serge Ngoma (knee)
- OUT: Peter Stroud (ankle)
- QUESTIONABLE: Emil Forsberg (illness)
Orlando City SC
- OUT: Ramiro Enrique (ankle)
- OUT: Mikey Halliday (knee)
- OUT: Robin Jansson (ankle)
- OUT: Tahir Reid-Brown (thigh)
Philadelphia Union
- OUT: Isaiah LeFlore (knee)
- OUT: Holden Trent (finger)
- QUESTIONABLE: Markus Anderson (ankle)
- QUESTIONABLE: Andre Blake (knee)
- QUESTIONABLE: Damion Lowe (back)
Portland Timbers
- OUT: Claudio Bravo (lower leg)
- OUT: Marvin Loria (knee)
Real Salt Lake
- OUT: Kevin Bonilla (knee)
- OUT: Bode Hidalgo (hamstring)
- OUT: Erik Holt (hamstring)
- OUT: Pablo Ruiz (knee)
- OUT: Marcelo Silva (hamstring)
- QUESTIONABLE: Andrew Brody (foot)
- QUESTIONABLE: Zavier Gozo (concussion)
- QUESTIONABLE: Bryan Oviedo (calf)
- OUT: Daniel Britto (lower body)
- OUT: JT Marcinkowski (knee)
- OUT: Jamar Ricketts (lower body)
- OUT: Josh Atencio (hamstring)
- OUT: Leo Chu (adductor)
- OUT: Nathan (quad)
- OUT: Braudilio Rodrigues (hamstring)
- QUESTIONABLE: Pedro de la Vega (hamstring)
- QUESTIONABLE: Yeimar Gómez Andrade (quad)
Sporting Kansas City
- OUT: Logan Ndenbe (knee)
- OUT: Kayden Pierre (ankle)
- QUESTIONABLE: Dany Rosero (quad)
- QUESTIONABLE: Remi Walter (knee)
- QUESTIONABLE: Josh Yaro (hamstring)
- QUESTIONABLE: Eduard Löwen (hamstring)
Toronto FC
- OUT: Shane O’Neill (thigh)
- OUT: Brandon Servania (thigh)
- QUESTIONABLE: Kevin Long (thigh)
- QUESTIONABLE: Jonathan Osorio (thigh)
Vancouver Whitecaps FC
- OUT: Sam Adekugbe (calf)
- OUT: Damir Kreilach (ankle)
