NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
- OUT: Stian Gregersen (concussion protocol)
- OUT: Jamal Thiaré (hamstring)
- OUT: Derrick Williams (calf)
- OUT: Tyler Wolff (knee)
Austin FC
- QUESTIONABLE: Ethan Finlay (hamstring)
- OUT: Brandon Cambridge (ankle)
- OUT: Liel Abada (thigh)
- OUT: Enzo Copetti (not due to injury)
- QUESTIONABLE: Bill Tuiloma (thigh)
- QUESTIONABLE: Ben Bender (knee)
- OUT: Chase Gasper (leg)
- OUT: Maren Haile-Selassie (leg)
- OUT: Tobias Salquist (leg)
- QUESTIONABLE: Gaston Giménez (leg)
- OUT: Yamil Asad (hamstring)
- OUT: Aaron Boupendza (jaw)
- QUESTIONABLE: DeAndre Yedlin (hip)
Colorado Rapids
- OUT: Daniel Chacón (knee)
- OUT: Kimani Stewart-Baynes (groin)
- QUESTIONABLE: Jonathan Lewis (knee)
- QUESTIONABLE: Djordje Mihailovic (not due to injury)
- OUT: Evan Bush (arm)
- QUESTIONABLE: Mo Farsi (groin)
FC Dallas
- OUT: Geovane Jesus (right knee)
- OUT: Amet Korça (groin)
- OUT: Sebastian Lletget (hamstring)
- OUT: Paxton Pomykal (knee)
- OUT: Alan Velasco (knee)
- QUESTIONABLE: Paul Arriola (calf)
D.C. United
- OUT: Russell Canouse (not due to injury)
Houston Dynamo FC
- OUT: Nelson Quiñónes (knee)
- OUT: Sebastian Ferreira (lower body)
- QUESTIONABLE: Franco Escobar (lower body)
- OUT: Lorenzo Dellavalle (right knee)
- OUT: Ryan Hollingshead (neck)
- OUT: David Martinez (back)
- OUT: None
Inter Miami CF
- OUT: Jordi Alba (hamstring)
- OUT: Shanyder Borgelin (hamstring)
- OUT: Facundo FarÃas (knee)
- OUT: Ian Fray (knee)
- OUT: Diego Gómez (ankle)
- OUT: Federico Redondo (knee)
- OUT: Robbie Robinson (knee)
Minnesota United FC
- Matchday 13 bye
- OUT: Matias Coccaro (knee)
- OUT: Grayson Doody (ankle)
- OUT: Raheem Edwards (abdomen)
- OUT: Ousman Jabang (adductor)
- OUT: Lassi Lappalainen (illness)
- OUT: Josef Martinez (knee)
- OUT: Mahala Opoku (ankle)
- OUT: Nathan Saliba (hip)
Nashville SC
- OUT: Lukas MacNaughton (ankle)
- OUT: Randall Leal (hip)
- QUESTIONABLE: Tyler Boyd (hip)
- QUESTIONABLE: Shaq Moore (hip)
- QUESTIONABLE: Walker Zimmerman (knee)
- OUT: Brandon Bye (knee)
- OUT: Nacho Gil (knee)
- OUT: DeJuan Jones (hamstring)
- OUT: Tommy McNamara (hamstring)
- OUT: Peyton Miller (foot)
- QUESTIONABLE: Jonathan Mensah (hamstring)
New York City FC
- OUT: Rio Hope-Gund (leg)
- OUT: Maxi Moralez (knee)
New York Red Bulls
- OUT: Ronald Donkor (back)
- OUT: Roald Mitchell (knee)
- OUT: Serge Ngoma (knee)
- OUT: Peter Stroud (ankle)
Orlando City SC
- OUT: Ramiro Enrique (ankle)
- OUT: Tahir Reid-Brown (thigh)
- OUT: Rafael Santos (shoulder)
- QUESTIONABLE: Dagur Dan Thórhallsson (concussion protocol)
Philadelphia Union
- OUT: Andre Blake (knee)
- OUT: Isaiah LeFlore (knee)
- QUESTIONABLE: Markus Anderson (leg)
- QUESTIONABLE: Olivier Mbaizo (calf)
- QUESTIONABLE: Cavan Sullivan (hip)
Portland Timbers
- OUT: Miguel Araujo (leg)
- OUT: Claudio Bravo (lower leg)
- OUT: Marvin Loria (knee)
Real Salt Lake
- OUT: Kevin Bonilla (knee)
- OUT: Zavier Gozo (concussion)
- OUT: Erik Holt (hamstring)
- OUT: Bryan Oviedo (calf)
- OUT: Pablo Ruiz (knee)
- OUT: Marcelo Silva (hamstring)
- QUESTIONABLE: Matt Crooks (oblique)
- OUT: Daniel Britto (lower body)
- OUT: JT Marcinkowski (knee)
- OUT: Jamar Ricketts (lower body)
- QUESTIONABLE: Bruno Wilson (upper body)
- OUT: Josh Atencio (hamstring)
- OUT: Nathan (quad)
- OUT: Braudilio Rodrigues (hamstring)
- QUESTIONABLE: Léo Chú (groin)
- QUESTIONABLE: Pedro de la Vega (hamstring)
- QUESTIONABLE: Yeimar Gómez Andrade (quad)
Sporting Kansas City
- OUT: Logan Ndenbe (knee)
- OUT: Kayden Pierre (ankle)
- QUESTIONABLE: Dany Rosero (quad)
- QUESTIONABLE: Remi Walter (knee)
- OUT: Josh Yaro (hamstring)
- QUESTIONABLE: Njabulo Blom (hamstring)
- QUESTIONABLE: Eduard Löwen (hamstring)
Toronto FC
- OUT: Richie Laryea (thigh)
- OUT: Jahkeele Marshall-Rutty (thigh)
- OUT: Shane O’Neill (thigh)
- OUT: Brandon Servania (knee)
Vancouver Whitecaps FC
- OUT: Sam Adekugbe (calf)
- OUT: Damir Kreilach (ankle)
